综合ICU院内感染回顾性分析

目的 探讨镇江市中西医结合医院综合ICU院内感染的发生率、院内感染患者的死亡率以及导致院内感染的危险因素及应对策略.方法 回顾分析2015年8月至2016年8月所有入住ICU患者的病历资料, 统计院内感染的发生率.对所有患者进行回顾性分析, 将感染患者作为观察组, 同期无感染患者作为对照组.比较2组患者在性别、年龄、APACHEII评分、入住ICU时间、血浆白蛋白水平、是否手术、是否存在意识障碍、有无侵袭性操作、是否预防性使用抗生素、是否合并其它基础疾病等可能危险因素方面的差异.对比2组患者病死率的差异.结果 医院感染发生率29.41%.2组在APACHEII评分、入住ICU时间、意识障碍、基础疾病、年龄、侵袭性操作差异有统计学意义 (P<0.05) ;在性别、血浆白蛋白水平、手术、预防性使用抗生素无统计学意义.院内感染的患者病死率 (40%) 明显高于对照组 (16.7%) , P<0.05.结论 病情危重程度、入住ICU时间、意识障碍、基础疾病、年龄、侵袭性操作对院内感染的发生有显著影响, 性别、血浆白蛋白水平、手术、预防性使用抗生素对院内感染的发生无影响.

A Retrospective Analysis of General ICU Nosocomial Infection

Objective To investigate the incidence of nosocomial infection in ICU, mortality rate of infected patients, the risk-factors and strategies of nosocomial infection. Me thods We retrospectively analyzed all ICU patients' medical records from August 2015 to August 2016, and the incidence of nosocomial infection. All patients were retrospectively analyzed, the infected patients as the observation group, the same period without infection as a control group. We compared the gender, age, APACHEII score, admission ICU time, plasma albumin levels, whether surgery, whether there were disturbance of consciousness, whether invasive operation, whether the use of antibiotics, whether combined with other underlying diseases and other risk factors between the two groups of patients. We also compared the differences in mortality between the two groups of patients. Re s ults The incidence of nosocomial infection was 29.41%. There were significant differences in APACHEII score, ICU time, disturbance of consciousness, underlying disease, age and invasive operation (P <0.05) . There was no statistically significant difference in sex, plasma albumin level, operation and prophylactic use of antibiotics significance. The mortality rate (40%) was significantly higher in hospital patients than in the control group (16.7%) (P<0.05) . Conclusion Severity of illness, ICU stay, unconsciousness, underlying disease, age, invasive procedures have a significant impact on the incidence of nosocomial infections, gender, serum albumin level, surgery, prophylactic use of antibiotics have no effect on the incidence of nosocomial infections.