经皮穿刺阴部神经电刺激治疗女性膀胱过度活动症的疗效观察

目的 女性膀胱过度活动症发病率逐年升高,但该病治疗手段单一,疗效一般,而本研究旨在积极探讨经皮穿刺阴部神经电刺激疗法治疗女性膀胱过度活动症的临床疗效,摸索该病治疗的新方法,造福更多患者。 方法 选取浙江中医药大学附属第二医院2015年1月-2017年2月收治的膀胱过度活动症女性患者60例,按随机数字表法随机分为观察组和对照组,每组各30例。在常规治疗的基础上,对照组给予口服酒石酸托特罗定缓释片治疗;观察组在对照组的基础上,继续给予经皮穿刺阴部神经电刺激治疗。3个月后观察患者平均24 h排尿次数、平均24 h尿失禁次数、膀胱过度活动症评分问卷表(overactive bladder symptom score,OABSS)评分、焦虑自评量表(self-rating anxiety scale,SAS)评分、生活指数评分。应用SPSS 22.0统计软件对数据进行分析。 结果 2组各疗效指标较治疗前均有改善,且观察组平均24 h尿失禁次数,OABSS、SAS及生活指数评分的改善程度明显优于对照组(均P<0.05),2组平均24 h排尿次数差异无统计学意义(P>0.05)。 结论 经皮穿刺阴部神经电刺激疗法能有效减少膀胱过度活动症患者平均24 h尿失禁次数,改善患者OABSS、SAS及生活指数评分,缓和患者焦虑状态,提高患者生活质量,疗效确切,且无明显不良反应,具有较高的安全性,值得临床推广,造福更多该病患者。 

Clinical observation of female overactive bladder patients through electrical stimulation on pudendal nerve by percutaneous puncture

Objective The incidence of overactive bladder (OAB) is increasing year by year, but the treatment of it is single. This study is intended to investigate the clinical efficacy of electrical stimulation on pudendal nerve by percutaneous puncture in female OAB patients. Methods Sixty cases of OAB patients were randomly divided into an observation group and a control group, 30 cases in each group. The control group was used oral tolterodine treatment, while the observation group was used electrical stimulation on pudendal nerve by percutaneous puncture as well as oral tolterodine treatment. After 3 months, the average urination and urinary incontinence times of 24 hours, overactive bladder syndrome score (OABSS), self-rating anxiety scale (SAS) and life index score of two groups were observed. SPSS 22.0 statistical software was applied to analyze the data. Results All therapeutic effect index of observation group and control group are improved compared to that before treatment. And the average urinary incontinence times of 24 hours, OABSS, SAS and life index score in observation group were significantly better than those in the control group (P<0.05). Conclusion Electrical stimulation on pudendal nerve by percutaneous puncture can effectively relieve symptoms of OAB and anxiety status. It is worth promoting for curative effect and high security.