MSCT对T1和T2期非小细胞肺癌患者纵隔淋巴结转移的诊断意义

  目的   评估胸部多层CT扫描（MSCT）对T₁和T₂期非小细胞肺癌（NSCLC）纵隔淋巴结转移的指导意义。   方法   选择2004年3月至2012年3月T₁和T₂期NSCLC患者32例,依据病理结果分析术前MSCT对纵隔淋巴结的判断。   结果   以淋巴结短径≥10 mm MSCT评价纵隔淋巴转移的敏感性和特异性分别为82.4%和92.4%;淋巴结大小、原发肿瘤位置及脏胸膜侵犯对纵隔淋巴转移的预测差异均有统计学意义（P < 0.05）。   结论   淋巴结大小可作为评估NSCLC患者纵膈淋巴结转移的依据,原发于右肺的肿瘤及肿瘤伴有脏层胸膜侵犯具有较高的纵隔淋巴结转移风险。 

Significance of MSCT in detecting mediastinal lymph node metastasis in T1 and T2 non-small cell lung cancer

  Objective   To evaluate multi-slice computer tomography (MSCT) in mediastinal lymph node metastasis of T₁ and T₂ non-small cell lung cancer (NSCLC).   Methods   A total of 32 patients with T₁ and T₂ NSCLC from February 2004 to October 2012 were selected. Preoperative MSCT assessment of mediastinal lymph nodes was performed on basis of the pathological results.   Results   Lymph nodes with diameters of ≥10 mm were evaluated, and the sensitivity and specificity of the MSCT mediastinal lymph node metastases were 82.4% and 92.4%, respectively. Lymph node size, primary tumor location, and visceral pleural invasion showed statistical significance in forecasting mediastinal lymph node metastases (P < 0.05).   Conclusion   MSCT can be used for the effective evaluation of mediastinal lymph node metastasis, lymph node size, and position of primary tumor. and visceral pleural invasion of the tumor had a higher risk of mediastinal lymph node metastasis.