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西洛他唑对糖尿病微血管病变的防治作用
引用本文:赵淑好,刘东晖,黄凌宁,严孙杰,杨立勇. 西洛他唑对糖尿病微血管病变的防治作用[J]. 中国综合临床, 2008, 24(9)
作者姓名:赵淑好  刘东晖  黄凌宁  严孙杰  杨立勇
作者单位:福建医科大学附属第一医院内分泌科,福州,350005
摘    要:目的 评价西洛他唑对糖尿病微血管病变的防治效果. 方法 对60例伴有微血管病变的糖尿病患者进行西洛他唑治疗1个月,观察其治疗前后平均血小板体积(MPV)、血小板压积(PCT)、血小板分布宽度(PDW)、血小板计数(PLT)四项指标的变化. 结果 西洛他唑治疗后微血管病变患者MPV、PDW明显下降,差异有统计学意义(均P<0.01). 结论 西洛他唑改善血小板基本参数,预防微血管病变的进展,对防治糖尿病微血管病变起着重要作用.

关 键 词:糖尿病微血管病变  西洛他唑  血小板

Effects of Cilostazol on microvascular complications of diabetic patients
ZHAO Shu-hao,LIU Dong-hui,HUANG Ling-ning,YAN Sun-jie,YANG Li-yong. Effects of Cilostazol on microvascular complications of diabetic patients[J]. Clinical Medicine of China, 2008, 24(9)
Authors:ZHAO Shu-hao  LIU Dong-hui  HUANG Ling-ning  YAN Sun-jie  YANG Li-yong
Abstract:Objecfive To evaluate the effects of cilostazol on the prevention of microvascular complications in diabetic patients.Methods 60 diabetic patients with microvascular complications were orally given cilostazol for 1 month.Changes of Mean platelet volume (MPV),plateletcrit (PCT),platelet distribution width (PDW) and platelet count (PLT) were studied.Results With administration of cilostazol,MPV and PDW decreased significantly. Conclusion Cilostazol improves platelet parameters,suggesting that it could prevent the progression of microvascular diseases.
Keywords:Microvascular complication of diabetes  Cilostazol  Platelet
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