门控心肌灌注显像心肌计数影响因素初探

目的探讨门控心肌灌注显像心肌计数的影响因素。方法选取100例静息态及负荷态门控心肌灌注显像正常的患者资料(男性47例,女性53例)。将原始图像重建后,采用感兴趣区(ROI)半定量分析方法,选取短轴显示左室心肌显示较完整的一帧图像,在左室心肌前壁勾画ROI,每个ROI的大小为10 pixels,将ROI的平均计数设定为每次检查的心肌计数。将患者的年龄、身高、体重、心率、显像时间与心肌计数进行相关性分析,将患者性别、负荷方式与心肌计数进行独立样本t检验,体重分组与心肌计数作单因素方差分析,将性别、体重、显像时间和心肌计数作多元线性回归分析。结果所有200例门控心肌灌注显像,性别之间的心肌计数(P=0.007),负荷方式之间的心肌计数(P=0.190)无统计学差异;对于相关性分析,心肌计数与体重呈中度负相关(r=-0.541,P=0.000)、与身高(r=-0.204,P=0.002)及显像时间(r=-0.168,P=0.009)均呈低度负相关,与心率(P=0.176)、年龄(P=0.502)不相关。结论影响门控心肌灌注显像心肌计数的重要因素为性别、体重、显像时间。可通过改进注射药量,规范显像时间,提高显像质量。

Primary study on the factors influencing the gated myocardial perfusion imaging myocardial count

Objective To explore the factors influencing the gated myocardial perfusion imaging myocardial count. Methods Select 100 patients with normal resting state and stressing state gated myocardial perfusion imaging（ 47 male,53 female）. After reconstructing the prime image,select a image on which the left ventricular muscle on the short axis,then draw the region of interested（ ROI） on the anterior wall of left ventricular muscle with the method of half quantitative analysis on the ROI,the size of each ROI is 10 pixels,and set the average count of ROI to the myocardium count checked every time. Get the patients＇ age,height,weight,heart rate,imaging time and myocardial counting for correlation analysis,Get the stress method,myocardial count and the patients＇ gender for independent samples T test,get the weight groups and myocardial count for single factor analysis,and get the patients＇ sex,weight,imaging time and myocardial counting for a multivariate linear regression analysis. Results Among the 200 gated myocardial perfusion imaging,the myocardium count are significantly different between the male and female patients（ P =0.007）,but the difference of the myocardium count is not significant between different loading ways（ P =0.190）; For correlation analysis,myocardium count is moderate correlated negatively with the weight（ r = 0. 541,P = 0. 000）,and have minor negative correlation with the height（ r = 0. 204,P = 0. 002） and the imaging time（ r = 0. 168,P = 0. 009）,but have no correlation with the heart rate（ P = 0. 176） or the age（ P = 0. 502）. Conclusion The important factors influencing the gated myocardial perfusion imaging of counting is the sex,weight and imaging time. The quality of the imaging can be improved by improving the injection dosage and standardizing the imaging time.