白芷提取物的稳定性研究

目的:通过乙醇提取法提取白芷有效成分,由白芷提取物的紫外光谱研究白芷提取物的稳定性。方法:使用紫外分光光度计确定白芷提取物的最大吸收波长,测定其最大吸光度。结果:白芷的提取物(呋喃香豆素类化合物)的最大吸收波长为299 nm,对时间和氧化剂的稳定性较好,光照下稳定性下降,随温度升高稳定性先增加后降低,不同pH值下溶液的吸光度改变不同,金属离子可以提高呋喃香豆素类化合物的稳定性。结论:白芷的乙醇提取物应尽量避光置于碱性条件久储,其本身抗氧化性较好,加入金属离子有利于提取物的长期存放。

Study on the stability of Angelica dahurica(Fisch ex. Hoffm. ) extract

Objective:to research the stability of the extract of Angelica dahurica(Fisch.ex.Hoffm.).by ultraviolet absorption change.Methods: A ultraviolet spectrophotometer was used to determine the maximum absorption wavelength and determine the biggest spectro-photometry of the extract.Results: Storage time had no influence on the stability of the extract,but the illumination,temperature,pH value,oxidant,metal ion of Cu2+ and Fe2+ and Fe3+ affect the biggest spectro-photometry of the extract.The best extraction process of Angelica dahurica(Fisch.ex.Hoffm.) was that extract tripled with 70% ethanol in a 1∶ 5 solid-liquid rate,every time three hours.The extract of Angelica dahurica(Fisch.ex.Hoffm.) is not stable under light,metal ion,PH value,the oxidant,the temperature,and attention should be paid to its storage.Conclusion:In order to store the extract for a longer time,the ethanol extract of Angelica is advised to be stored in a dark environment which is alkaline.