| 内皮素在评价不阻断升主动脉低温室颤对心肌保护作用中的应用 |
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| 引用本文： | 关晓海,李占清,陈国生,张宇,蒲国华,陈晨. 内皮素在评价不阻断升主动脉低温室颤对心肌保护作用中的应用[J]. 华北煤炭医学院学报, 2004, 6(4): 413-415 |
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| 作者姓名： | 关晓海 李占清 陈国生 张宇 蒲国华 陈晨 |
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| 作者单位： | 华北煤炭医学院附属医院胸外科,河北唐山,063000 |
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| 摘 要： | ①目的探讨体外循环条件下低温室颤技术对心肌的保护作用。②方法14只健康成年犬随机分为两组，低温停跳组(n=7)与低温室颤组(n=7)，分别检测两组手术前、手术1、2小时和复跳后1小时4个时间点血内皮素(ET)的水平。③结果室颤组ET水平明显低于停跳组。④结论通过内皮素水平的变化，说明体外循环条件下低温室颤技术是一种安全、有效的心肌保护方式，优于传统低温停跳技术。
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| 关 键 词： | 低温室颤 心肌保护 内皮素 |
| 文章编号： | 1008-6633(2004)04-0413-03 |
| 修稿时间： | 2004-04-10 |
Evaluation of myocardial preservation by hypothermic ventricular fibrillation without aortic cross-clamping through the levels of ET |
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| GUAN Xiaohai,LI Zhanqing,CHEN Guosheng,et al.. Evaluation of myocardial preservation by hypothermic ventricular fibrillation without aortic cross-clamping through the levels of ET[J]. Journal of North China Coal Medical College, 2004, 6(4): 413-415 |
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| Authors: | GUAN Xiaohai LI Zhanqing CHEN Guosheng et al. |
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| Abstract: | Objective To investigate the protective effect of hypothermic ventricular fibrillation on myocardium. Methods Fourteen adult mongrel dogs were randomly divided into two groups: Cold Crystalleid group (Group CC, n=7) and Hypothermic Ventricular Fibrillation group (Group HF, n=7). The levels of ET in blood were tested before operation ,at 1, 2 hours during operation and 1 hour after heart beating. Results In Group HF , the levels of ET were significantly lower than Group CC . Conclusions The technique of hypothermic ventricular fibrillation is a safe and effective strategy to protect the myocardium and superior to the cold crystalleid cardioplegia. |
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| Keywords: | Hypothermic ventricular fibrillation Myocardial protection Endothelin |
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