| 四物汤及其配伍组方中苯甲酸煎出量的HPLC法测定 |
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| 引用本文： | 容蓉,袁久荣.四物汤及其配伍组方中苯甲酸煎出量的HPLC法测定[J].中草药,2001,32(2):114-115. |
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| 作者姓名： | 容蓉 袁久荣 |
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| 作者单位： | 山东中医药大学天然药物省重点实验室，山东济南 250014 |
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| 基金项目： | 国家自然科学基金资助项目，项目编号 39670867 |
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| 摘 要： | 目的：考察四物汤中白芍与其它各单味药排列组合构成的８种样本药中 苯甲酸煎出量的变化。方法ＲＰ－ＨＰＬＣ法进行测定。结果白芍单味药苯甲酸剪出量为２．７４mg/g；加其它药味合煎后，苯甲醛煎出量为０．４１－１．１１mg/g。结论白芍单煎，苯甲酸剪出量较高；而与四物汤中其它药味合煎后，可显著降低苯甲酸的剪出量。
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| 关 键 词： | 四物汤 配伍 苯甲酸 RP－HPLC 测煎出量 中药 |
| 文章编号： | 0253-2670(2001)02-0114-02 |
| 收稿时间： | 2000/3/16 0:00:00 |
| 修稿时间： | 2000年3月16日 |
Determination of content of benzoic acid in SIWUTANG by RP-HPLC |
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| RONG Rong and YUAN Jiu rong.Determination of content of benzoic acid in SIWUTANG by RP-HPLC[J].Chinese Traditional and Herbal Drugs,2001,32(2):114-115. |
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| Authors: | RONG Rong and YUAN Jiu rong |
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| Institution: | Key Laboratory of Natural Products, Shandong University of TCM, Ji'nan Shandong 250014, China;Key Laboratory of Natural Products, Shandong University of TCM, Ji'nan Shandong 250014, China |
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| Abstract: | Object To determine the change of benzoic acid conte nts indecoctions prepared from various combinations of the recipe named SIWUTANG by RP-HPLC to provide a reference for the control of the acid level. Methods 8 decoctions of P. lactiflora either a l one or in combination with one or more of the other 3 components, according to p ermutation and combination, were prepared and their benzoic acid contents determ i ned by RP-HPLC. Results The content of benzoic acid in the de co ction of Radix Paeonie Alba alone was found to be 2.74 mg/g, wh il e that of the other 7 combinations varied from 0.41～1.11 mg/g. Conclusion The content of benzoic acid in SIWUTANG could be low ered significantly by the presence of Radix Angelica Sinensis, Radix Reh manniae, and Rhizoma Chuanxiong. |
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| Keywords: | SIWUTANG compatibility benzoic acid RP-HPLC |
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