| Abstract: | The effect of an increase in the oxygen pressure (6 atm) on the content of the polyamines spermine and spermidine in the rat brain and liver was investigated. During the period of oxygen convulsions and 4 h after decompression the spermidine concentration in the brain and liver was reduced. The spermine concentration in the brain also was reduced during the period of convulsions, but 4 h after decompression it was significantly increased, although, still below the control level. The spermine level in the liver was unchanged during oxygen convulsions, but rose sharply during the next 4 h. The role of polyamines in the regulation of protein biosynthesis during hyperoxia is discussed.Department of Biochemistry, Rostov-on-Don University. (Presented by Academician of the Academy of Medical Sciences of the USSR V. N. Chernigovskii.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 85, No. 1, pp. 28–30, January, 1978. |
