原发性醛固酮增多症与原发性高血压的电解质特点比较

目的比较原发性醛固酮增多症（PA）与原发性高血压（EH）的电解质特点。方法分析2000年3月-2010年6月我科以高血压原因待查入院患者的电解质特点,其中PA 202例,EH 67例。结果 PA组血钾、血钙明显低于EH组（P〈0.01）,血钠、二氧化碳结合力、血醛固酮（Ald）、尿醛固酮（Urinary Ald）显著高于EH组（P〈0.01）。血钾正常的PA组与EH组,前者血钾低于后者（P〈0.01）,血钠、Ald、Urinary Ald明显高于后者（P〈0.01）。结论总体上PA的低血钾、低血钙、高血钠、高二氧化碳结合力有助于与EH的鉴别。

Characteristics of electrolytes in primary aldosteronism and essential hypertension: A comparative study

Objective To compare the characteristics of electrolytes in primary aldosteronism（PA） and essential hypertension（EH）.Methods Characteristics of electrolytes in 202 PA and 67 EH patients admitted to our department from March 2000 to June 2010 were retrospectively analyzed.Results The serum potassium and calcium levels were significantly lower in PA patients than in EH patients（P〈0.01）.The serum natrium,plasma aldosterone,urinary aldosterone levels and CO2CP were significantly higher in PA patients than in EH patients（P〈0.01）.The serum potassium level was lower in PA patients without hypokalemia than in EH patients without hypokalemia（P〈0.01）,while the serum natrium,plasma aldosterone and urinary aldosterone were significantly higher in PA patients without hypokalemia than in EH patients without hypokalemia（P〈0.01）.Conclusion Generally speaking,the serum potassium,natrium,calcium levels and CO2CP are different in PA and EH patients.