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胃癌术后患者预后相关因素分析
引用本文:刘利利,韩颖,路长宇,胡守喜,杜晓辉. 胃癌术后患者预后相关因素分析[J]. 军医进修学院学报, 2011, 32(6): 584-587
作者姓名:刘利利  韩颖  路长宇  胡守喜  杜晓辉
作者单位:1. 解放军总医院普通外科研究所,北京,100853
2. 邯郸市第一医院中西医结合内科,邯郸,056000
3. 北京市门头沟区医院外科,北京,102300
4. 山西省肿瘤医院特诊科,太原,030013
摘    要:目的探讨性别、年龄、肿瘤临床TNM(T肿瘤大小、N淋巴结转移、M远处转移)分期、化疗及危重病人预警蛋白质(LGT)指纹表达等与胃癌术后患者预后的关系。方法选取2008年6月-2009年6月收治的首次入院并行手术治疗的胃腺癌患者125例,选择性别、年龄、肿瘤临床TNM分期、化疗、LGT蛋白质指纹表达等指标,用单因素和多因素分析的方法研究其对患者生存的影响。结果单因素分析中肿瘤临床TNM分期、LGT丰度、峰型均为胃癌患者术后生存的影响因素。将上述诸相关参数进行COX比例风险回归模型分析,得出TNM分期、LGT蛋白质指纹丰度及峰型是影响胃癌术后患者生存的独立因素,按其影响大小依次排序为:TNM分期、LGT峰型、LGT丰度。结论肿瘤临床TNM分期、LGT峰型、LGT丰度是影响胃癌患者术后生存的独立因素。

关 键 词:胃癌  生存分析  LGT蛋白质指纹

Related factors for prognosis of gastric cancer patients after operation
LIU Li-li,HAN Ying,LU Chang-yu,HU Shou-xi,DU Xiao-hui. Related factors for prognosis of gastric cancer patients after operation[J]. Academic Journal of Pla Postgraduate Medical School, 2011, 32(6): 584-587
Authors:LIU Li-li  HAN Ying  LU Chang-yu  HU Shou-xi  DU Xiao-hui
Affiliation:LIU Li-li1,HAN Ying2,LU Chang-yu3,HU Shou-xi4,DU Xiao-hui1 1Institute of General Surgery,Chinese PLA General Hospital,Beijing 100853,China,2Department of Integrated Traditional and Western Medicine,Handan First Hospital,Handan 056000,Hebei Province,3Department of Surgery,Beijing Mentougou Hospital,Beijing 102300,4Department of Special Diseases,Shanxi Provincial Tumor Hospital,Taiyuan 030013,Shanxi Province
Abstract:Objective To study the correlation between gender and age of gastric cancer patients,clinical TNM stage,chemotherapy,lost goodwill target(LGT) protein fingerprints and prognosis of gastric cancer patients after operation.Methods One hundred and twenty-five patients with gastric adenocardnoma admitted to our hospital in June 2008-June 2009 were enrolled in this study.Effect of their gender,age,TNM stage,chemotherapy,and LGT protein fingerprints on their survival time after operation was analyzed by single an...
Keywords:Gastric Cancer  Survival Analysis  LGT Fingerprints  
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