| 儿童遗传性球形红细胞增多症中MCHC的特异性 |
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| 引用本文： | 傅岩,刘曙光. 儿童遗传性球形红细胞增多症中MCHC的特异性[J]. 军医进修学院学报, 2011, 32(6): 594-595 |
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| 作者姓名： | 傅岩 刘曙光 |
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| 作者单位： | 首都医科大学附属北京儿童医院血液病中心血检室,北京,100045 |
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| 摘 要： | 目的观察红细胞指数平均红细胞血红蛋白浓度（Mean Corpuscular Hemoglobin Concentration,MCHC）在儿童遗传性球形红细胞增多症中的特异性。方法应用Sysmex SE-9000全自动血液分析仪检测初诊遗传性球形红细胞增多症（Hereditary Spherocytosis,HS）、自身免疫性溶血性贫血（Autoimmune Hemolytic Anemia,AHA）、巨幼红细胞性贫血（Megaloblastic Anemia,MA）、缺铁性贫血（Iron Deficiency Anemia,IDA）患儿和对照组（儿童）各50例的MCHC。结果 HS患者MCHC显著高于其他疾病组和健康对照组（P〈0.05）,MCHC临界值为355g/L时,MCHC诊断HS的灵敏度和特异性分别为87.76%和98.00%。余各组间MCHC差异无统计学意义（P〉0.05）。结论 MCHC增高的特异性,对临床诊断HS有重要提示意义。
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| 关 键 词： | 平均红细胞血红蛋白浓度 遗传性球形红细胞增多症 特异性 |
Specificity of mean corpuscular hemoglobin concentration in children with hereditary spherocytosis |
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| FU Yan,LIU Shu-guang. Specificity of mean corpuscular hemoglobin concentration in children with hereditary spherocytosis[J]. Academic Journal of Pla Postgraduate Medical School, 2011, 32(6): 594-595 |
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| Authors: | FU Yan LIU Shu-guang |
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| Affiliation: | Hematopathy Center,Beijing Children′s Hospital,Capital Medical University,Beijing 100045,China |
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| Abstract: | Objective To observe the specificity of mean corpuscular hemoglobin concentration(MCHC) in children with hereditary spherocytosis(HS).Methods MCHC was measured in 50 children with newly diagnosed HS(HS group),50 children with autoimmune hemolytic anemia(AHA group),50 children with iron deficiency anemia(IDA group),50 children with megaloblastic anemia(MA group) and 50 healthy controls(control group) using a Sysmex SE-9000 automatic blood cells analyser.Results The MCHC was significantly higher in HS group t... |
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| Keywords: | Mean Corpuscular Hemoglobin Concentration Hereditary Spherocytosis Specificity |
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