前列腺素E1治疗不稳定型心绞痛局部不良反应的观察与护理

目的观察前列腺素E1（PGE1）在治疗不稳定型心绞痛的副作用,探讨护理干预的效果。方法将我院2009年1月-2010年6月不稳定型心绞痛住院患者153例随机分为两组,对照组（76例）使用PGE1 10μg静滴,观察组（77例）在静滴PGE1 10μg前使用德莫林外敷并抬高输液肢体30cm,观察两组用药后的不良反应。结果观察组在改善患者疼痛、静脉炎及肿胀方面优于对照组（P〈0.05）。结论前列腺素E1治疗不稳定型心绞痛患者时采用德莫林外敷并抬高输液肢体的护理干预对于改善局部不良反应具有良好效果。

Local adverse reactions in unstable angina patients after treated with PGE1

Objective To observe the adverse reactions in unstable angina（UA） patients after treated with PGE1 and study the effect of nursing intervention on them.Method One hundred and fifty-three UA patients admitted to our hospital from January 2009 to June 2010 were randomly divided into control group（n=76） and observation group（n=77）.Patients in control group were treated with intravenous drip of 10μg PGE1,and those in observation group were treated with local dermlin dressing with their limbs raised before intravenous drip of 10μg PGE1.Adverse reactions were observed in two groups.Results The pain,phlebitis and swelling were improved much better in observation group than in control group（P〈0.01）.Conclusion Nursing intervention with dermlin local dressing and raising limbs can decrease the local adverse reactions in UA patients after treated with PGE1.