Laminin distribution in human decidua and immature placenta. An immunoelectron microscopic study (avidin-biotin-peroxidase complex method) |
| |
| Authors: | C Charpin F Kopp N Pourreau-Schneider J C Lissitzky M N Lavaut P M Martin M Toga |
| |
| Affiliation: | 1. Carnegie Mellon Unviersity, 5000 Forbes Ave, Pittsburg, PA 15213, USA;2. School of Computing, National University of Singapore, 15 Computing Drive, Singapore 117418;3. School of Business, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-749, Republic of Korea;1. Alessandrescu-Rusescu National Institute for Mother and Child Health, Fetal Medicine Excellence Research Center, Bucharest, Romania;2. Division of Obstetrics, Gynecology and Neonatology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania;3. Department of Obstetrics and Gynecology, Polizu Clinical Hospital, Alessandrescu-Rusescu National Institute for Mother and Child Health, Bucharest, Romania;4. Department of Cell and Molecular Biology and Histology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania;5. Department of Surgical Oncology, Prof. Dr. Alexandru Trestioreanu Oncology Institute, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania |
| |
| Abstract: | An immunoelectron microscopic study was carried out on human placenta and decidua with the use of preembedding, the avidin-biotin-peroxidase complex technique, and rabbit anti-murine laminin antibody. Laminin was detected in the lamina lucida of basement membrane of placental villi, amniotic membranes, umbilical cord, endometrial glands, and blood vessels. No positive laminin immunostaining was observed in intracytoplasmic organelles. However, positive immunostaining surrounded decidual cells as a more or less continuous linear membrane. It is suggested that laminin, as a component of this basement membrane-like material that has already been reported in decidual cells, may be related to the hormonal stimulation occurring during pregnancy and trophoblastic attachment. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
