A case of renal angiomyolipomas associated with multiple and various hamartomatous microlesions |
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Authors: | Yoji Nagashima Yoshiharu Ohaki Yukichi Tanaka Kazuaki Misugi Masuo Horiuchi |
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Institution: | (1) Department of Pathology, Yokohama City University School of Medicine, 3-9, Fukuura, 236 Kanazawa-ku, Yokohama, Japan;(2) Department of Urology, Kanagawa Prefectual Ashigara-Kami Hospital, 866-1, Sohryoh, Matsuda-machi Ashigarakami-gun, 258 Kanagawa, Japan |
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Abstract: | Summary A case of 50-year-old woman who demonstrated large intrarenal and externally protruding angiomyolipomas (AMLomas), unusual intraglomerular lesions and multiple hamartomatous microlesions of various types within the kidney is reported. This type of intraglomerular lesion has been briefly described only twice previously in patients with tuberous sclerosis (TS), and is unique in its location and histological appearance. The lesions are mainly composed of proliferating mesangial cells and are hamartomatous in nature. Although no stigmata of TS other than renal AMLomas are apparent in this case, the presence of many renal hamartomatous lesions suggests the possibility of a forme fruste of TS. |
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Keywords: | Intraglomerular lesions Renal angiomyolipoma (AMLoma) Tuberous sclerosis (TS) Forme fruste of TS |
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