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Results of ASERTAA,a Randomized Prospective Crossover Pharmacogenetic Study of Immediate-Release Versus Extended-Release Tacrolimus in African American Kidney Transplant Recipients
Authors:Jennifer Trofe-Clark  Daniel C. Brennan  Patricia West-Thielke  Michael C. Milone  Mary Ann Lim  Robin Neubauer  Vincenza Nigro  Roy D. Bloom
Affiliation:1. Department of Pharmacy Services, Hospital of the University of Pennsylvania, Philadelphia, PA;2. Renal Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA;3. Washington University School of Medicine, St. Louis, MO;4. University of Illinois, Chicago, IL;5. Perelman School of Medicine, University of Pennsylvania, Penn Institute for Immunology, Philadelphia, PA;6. Veloxis Pharmaceuticals, Edison, NJ
Abstract:
Keywords:Immunosuppression  tacrolimus  kidney transplantation  pharmacogenetics  tacrolimus dosing  randomized clinical trial  African American ancestry  genetic differences  pharmacokinetics  drug absorption  genotype
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