首页 | 本学科首页   官方微博 | 高级检索  
检索        


Finite element modeling of the thoracic aorta: including aortic root motion to evaluate the risk of aortic dissection
Authors:C J Beller  M R Labrosse  M J Thubrikar  F Robicsek
Institution:1. Department of Cardiac Surgery, University Hospital Heidelberg, INF 326, 69120, Heidelberg, Germanycarsten.beller@urz.uni-heidelberg.de;3. University of Ottawa, Department of Mechanical Engineering, Ottawa, Ontario, K1N 6N5, Canada;4. Edwards Life Sciences, Irvine, California, 92614, USA;5. Carolinas Medical Center, Charlotte, North Carolina, 28203, USA
Abstract:Objective: We propose that the aortic root motion plays an important role in aortic dissection.

Methods and results: A finite element model of the aortic root, arch and branches of the arch was built to assess the influence of aortic root displacement and pressure on the aortic wall stress. The largest stress increase due to aortic root displacement was found at approximately 2 cm above the top of the aortic valve. There, the longitudinal stress increased by 50% to 0.32 MPa when 8.9 mm axial displacement was applied in addition to 120 mmHg luminal pressure. A similar result was observed when the pressure load was increased to 180 mmHg without axial displacement.

Conclusions: Both aortic root displacement and hypertension significantly increase the longitudinal stress in the ascending aorta, which could play a decisive role in the development of various aortic pathologies, including aortic dissection.
Keywords:Aortic root motion  Mechanical stress  Aortic dissection
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号