| 大,小肝细胞癌的DNA定量比较 |
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| 引用本文： | 赵景民 张中华. 大,小肝细胞癌的DNA定量比较[J]. 滨州医学院学报, 1996, 19(5): 428-429 |
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| 作者姓名： | 赵景民 张中华 |
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| 作者单位： | 上海市肿瘤研究所 |
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| 摘 要： | 为研究小肝细胞（ＳＨＣＣ）丐大肝细胞癌（ＬＨＣＣ）细胞生物学特片的差异，采用ＱＤＡ软件分析系统对１１例ＳＨＣＣ和２０例ＬＨＣＣ作ＤＮＡ定量比较。结果显示，８例（７２．７％）ＳＨＣＣ为二倍体细胞（２Ｃ）例（１９例（９５．０％）ＬＨＣＣ是异倍体（ＡＮ）型（Ｐ〈０．０１）。１７例（８５．０％）ＬＨＣＣ的ＤＮＡ直方图为多峰曲线，而９例（８１．８％）ＳＨＣＣ为单峰曲线（Ｐ〈０．０１）。结果表明，ＳＨＣＣ主要
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| 关 键 词： | DNA 肝细胞癌 图象分析 |
QUANTITATIVE COMPARISON OF DNA CONTENT BETWEEN SMALL AND LARGE HEPATOCELLULAR CARCINOMA |
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| Zhao Jingmin,et al. QUANTITATIVE COMPARISON OF DNA CONTENT BETWEEN SMALL AND LARGE HEPATOCELLULAR CARCINOMA[J]. Journal of Binzhou Medical College, 1996, 19(5): 428-429 |
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| Authors: | Zhao Jingmin et al |
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| Abstract: | To study the biologicaf characteristics of small hepatocellular carcinoma(SHCC) and large hepatocellular carcinoma(LHCC),the DNA centent of 11 SHCC and 20 LHCC was guantitatively determined by means of QDA-image analysis. The results showed that 8(72. 2%)SHCC had DNA cell line in diploid(2C),and 19(95. 0%) LHCC had DNA cell line in aneuploid(AN)(P<0. 01). The multipeak histogram of DNA content in LHCC was 85. 00%,but the single peak histogram in SHCC was 81. 80% (P<0.01 ). The results suggest that the majority of SHCC is monoclonal 2C cell line,and LHCC is mainly AN cell line with heterogeneity. |
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| Keywords: | DNA hepatocellular carcinoma image analysis |
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