Case of primary biliary cirrhosis-autoimmune hepatitis overlap which manifested after delivery |
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Authors: | Monoe Kyoko Takahashi Atsushi Katsushima Fumiko Kanno Yukiko Saito Hironobu Abe Kazumichi Yokokawa Junko Ohira Hiromasa |
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Institution: | Department of Gastroenterology and Rheumatology, Fukushima Medical University School of Medicine, Japan. |
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Abstract: | A 34-year-old woman showed liver dysfunction for the first time at 3 months after delivery. Two years later, she was referred to our department with continued liver dysfunction. She fulfilled the criteria for primary biliary cirrhosis (PBC)-autoimmune hepatitis (AIH) overlap. Liver dysfunction improved after administration of ursodeoxycholic acid and bezafibrate. To the best of our knowledge this represents the second report of PBC-AIH overlap after delivery and we discuss immunological changes during the perinatal period. |
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