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Case of primary biliary cirrhosis-autoimmune hepatitis overlap which manifested after delivery
Authors:Monoe Kyoko  Takahashi Atsushi  Katsushima Fumiko  Kanno Yukiko  Saito Hironobu  Abe Kazumichi  Yokokawa Junko  Ohira Hiromasa
Institution:Department of Gastroenterology and Rheumatology, Fukushima Medical University School of Medicine, Japan.
Abstract:A 34-year-old woman showed liver dysfunction for the first time at 3 months after delivery. Two years later, she was referred to our department with continued liver dysfunction. She fulfilled the criteria for primary biliary cirrhosis (PBC)-autoimmune hepatitis (AIH) overlap. Liver dysfunction improved after administration of ursodeoxycholic acid and bezafibrate. To the best of our knowledge this represents the second report of PBC-AIH overlap after delivery and we discuss immunological changes during the perinatal period.
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