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左旋精氨酸在食管癌治疗中的作用
引用本文:秦子敏,郅兴义,赵松. 左旋精氨酸在食管癌治疗中的作用[J]. 中国肿瘤临床, 2000, 27(8): 591-593
作者姓名:秦子敏  郅兴义  赵松
作者单位:河南省肿瘤医院胸外科 郑州市 450003
摘    要:目的:探讨左旋精氨酸在食管癌治疗中的作用。方法:86例患者随机分为两组,实验组术前15天静脉输注左旋精氨酸0.5kg/kg天,然后手术。标本行细胞凋亡检查,与对照组对比。结果:实验组肿瘤细胞凋亡阳经明显高于对照组。结论:左旋中引起食管癌细胞的凋亡,在管癌治疗中的有一定作用。

关 键 词:食管癌 左旋精氨酸 一氧化氮 细胞凋亡
修稿时间:1999-07-06

Effects of L-arginine in Patients with Esophageal Carcinoma
Qin Zimin Zhi Xingyi Zhao Song. Effects of L-arginine in Patients with Esophageal Carcinoma[J]. Chinese Journal of Clinical Oncology, 2000, 27(8): 591-593
Authors:Qin Zimin Zhi Xingyi Zhao Song
Affiliation:Qin Zimin Zhi Xingyi Zhao Song Department of Surgery,Henan Provincial Cancer Hospital,Zhengzhou
Abstract:Objective:To study the effects of L arginine for patients with esophageal cancer.Methods:Eighty six patients were randomly divided into two groups:each of 43 cases in experimental group and control group.L arginine was given at 0.5g/kg/d iv for 15 days prior to operation of the experimental group.Apoptosis in these samples were detected by terminal labeling method and compared with control group.Results:It showed that apoptosis cell in experimental group siginificantly increased than that in control group.Conclusion:It suggests that L arginine plays an important role in the treatment of esophageal carcinoma.
Keywords:Esophageal carcinoma Apoptosis L arginine Nitric oxide
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