中老年人群血清胆固醇水平及其相关因素的研究

目的　探讨中老年“健康”人群血清总胆固醇 (TC)、高密度脂蛋白—胆固醇 (HDL- C)、低密度脂蛋白—胆固醇 (L DL- C)水平及与相关个体因素的关系。方法　随机抽取 340人 ,横断面调查方法进行问卷调查、体格检查和血脂水平测定。结果　 4 5岁以上的 340人 (男 183人、女 15 7人 )血清胆固醇水平均在正常范围内 ;女性 TC、HDL- C及 L DL- C水平均显著高于男性 (P<0 .0 5 ) ;70岁以上老人 HDL- C水平均显著高于其它年龄组。逐步回归分析显示 :显著影响 TC水平的个体因素为年龄、性别 ,影响 L DL- C的因素为年龄、性别和体重指数 (BMI) ,影响 HDL- C水平的因素为年龄、饮酒、BMI。结论　超重和肥胖、经常大量饮酒是升高血胆固醇的重要因素。健康教育和行为干预过程中应强调良好的生活方式和维持适当的体重。

Relationship between Lifestyle and Serum Cholesterol in Middle-old Age Men

Objective To study the relationship between lifestyle and serum total cholesterol (TC),low-density lipoprotein cholesterol (LDL-C),high-density lipoprotein cholesterol (HDL-C). Methods It was a cross-sectional study. Self-administered questionnaires and serum lipid levels were performed in 340 middle-old age men without any clinical appearance of cardiovascular diseases or lipid metabolism disorder. Results Compared with men, the levels of TC,HDL-C,LDL-C in women were significant higher.The serum level of HDL-C in the elder over 70 years men, whether male or female,was higher than that of others,P<0.05. From stepwise regression analyses, significant correlation with TC, LDL-C and HDL-C were,age and sex for TC; BMI, age and sex for LDL-C; BMI(negative), alcohol intake (negative) and age for HDL-C.Conclusions Overweight and obesity are still main factors that affect on serum cholesterol level in middle-old aged peope.Both a fit MBI and a good daily lifestyles are important for regulating blood lipid levels.