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肝癌经皮门静脉时辰化疗的疗效观察
引用本文:李凌 吴建兵 兰琼玉 徐华 冯龙 王顺金 黄平. 肝癌经皮门静脉时辰化疗的疗效观察[J]. 实用临床医学(江西), 2005, 6(7): 23-24
作者姓名:李凌 吴建兵 兰琼玉 徐华 冯龙 王顺金 黄平
作者单位:江西医学院第二附属医院肿瘤科 江西南昌330006(李凌,吴建兵,兰琼玉,徐华,冯龙,王顺金),江西医学院第二附属医院肿瘤科 江西南昌330006(黄平)
基金项目:江西省科委课题(20041B0303100)
摘    要:目的:探讨不能手术切除的中晚期肝癌的治疗新途径。方法:对18例肝癌患者在TACE治疗后再经皮穿刺门静脉置管,采用微电脑控制的全自动注药盒每天在特定的时间向门静脉内注入DDP及以正弦曲线速率注入5-Fu进行时辰化疗,对生存时间进行观察比较。结果:生存期延长;AFP阳性病人的肿瘤标记物AFP大幅度下降;3例门静脉癌栓病人有2例癌栓消失。结论:门静脉置管时辰化疗联合TACE治疗中晚期肝癌疗效较为满意。

关 键 词:肝肿瘤 门静脉 时辰化疗
文章编号:1009-8194(2005)07-0023-02
修稿时间:2005-04-05

Purcutaneous Portal Vein Chronomodulated Chemotherapy on Treatment of Liver Cancer
Li Ling,Wu Jian-bing,Lan Qiong-yu,Xu Hua,Feng Long,Wang Shun-jin,Huang Ping. Purcutaneous Portal Vein Chronomodulated Chemotherapy on Treatment of Liver Cancer[J]. Practical Clinical Medicine, 2005, 6(7): 23-24
Authors:Li Ling  Wu Jian-bing  Lan Qiong-yu  Xu Hua  Feng Long  Wang Shun-jin  Huang Ping
Abstract:Objective:To explore a new therapeutics on patients with un ab le surgical excisional advanced liver cancer.Metheds:After TACE treatment,18 pat ients with advanced liver cancer were treated by means of the portal vein chrono modulated chemotherapy by which DDP and 5-Fu was infused into the portal vein through the inserted catheter;survival was observed.Results:Survival period was longer;AFP was reduced remarkable;carcinous thrombus in the master portal v ein was missed on two patients among three.Conclusion:It is demonstrated that po rtal vein chronomodulated chemotherapy combined with TACE on treatment of liver cancer is an effective therapy.
Keywords:liver neoplasm  portal vein  chronomodulated chemotherapy
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