| Abstract: | The avirulent “A8” strain of S.F.V. gave rise to acute lesions of encephalitis in mice within 7 days of infection. After 6 weeks, however, all signs of disease disappeared from the brain, but when such animals were destroyed 2 years later they had advanced lesions of hydrocephalus, spongy degeneration and above all a severe astrocytic reaction in many centres of the brain. No such lesions were observed either in animals inoculated with formolinactivated virus, or in uninoculated controls of the same age. |
