MCE多巴酚丁胺负荷试验在冠心病诊断中的应用价值

目的评价MCE药物负荷试验在冠心病诊断中的价值。方法49例住院患者进行了常规超声心动图、基础状态下和中剂量多巴酚丁胺负荷状态下的心肌声学造影以及选择性冠状动脉造影。结果49例患者中冠脉造影15例异常,15例异常患者基础状态下,66.7%的冠状动脉病变其相应的心肌阶段组织灌注水平较正常减低,33.3%的冠状动脉病变心肌灌注水平与正常相似。负荷状态下,几乎所有冠状动脉病变,其相应的心肌阶段组织灌注水平异常,且灌注异常阶段增多,计分减少。结论MCE药物负荷试验可以作为一项安全、敏感的冠状动脉疾病检查方法用于冠心病临床诊断。

Value of low dose dobutamine real-time myocardial contrast echocardiography in the assessment of coronary artery disease

Objective To evaluate the value of real-time myocardial contrast echocardiography (RT-MCE) combined with middle dose dobutamine stress test in the detection of coronary artery disease (CAD ).Methods 49 hospitalized patients referred for coronary angiography and subsequent revascularization underwent rou- tine echocardiography, RT-MCE at baseline and after low dose dobutamine administration. The images of RT-MCE were analyzed quantitatively from microbubble replenishment curves formyocardial perfusion.Results After coronary angiography,among the 49 patients,15 appeared f coronary arterial stenosis,the degree of coronary arterial stenosis of 15 patients was from 50% to 95%. In the 15 case of coronary artery stenosis, At baseline, compared with the coronary angiography, it was showed that there was a no significant myocardial perfusion reduced showed in MCE study in 33. 3% patients.Under dobutamine stress, it was showed that there was a significant myocardial perfusion reduced showed in MCE study in all patients,while the number of segment increase and the score index decrease.Conclusion RT-MCE in conjunction with dobutamine stress can be used as a sensitive measure to identify and stratify CAD as well as to assess the contribution of collateral blood flow.