肺叶切除时不同方法处理支气管残端的动物实验

目的:从病理形态学角度,比较肺切除术后不同方法闭合的支气管残端的愈合全过程。方法:对15条犬先后实施三次剖胸多肺叶切陈术(90例);并在离体的犬主、叶支气管上制作残端模型(75个/次);残端分别用开放式sweet's法、器械法及结扎法关闭。动态观察以病理形态学为主的三种残端的愈合过程及相关指标。结果:与缝合者比较,结扎法手术耗时短(P<0.01);结扎者耐压性能好(P<0.01);不加深残端盲袋(P>0.05);形态学表现为愈合早、快、好。结论:结扎后的残端愈合在多方面优于缝合者。

Experimental Study on the Closure of Bronchial Stumps Following Pulmonary Resection by Different Techniques

Little is known about the advantages and the disadvantages of different techniques for bronchial stump closure following pulmonary resection in a controlled study. In this experimental study 90 lobectomies were performed on 15 mangrel dogs, weighting 11-20 kg, and 165 bronchial stumps were dealed with three different methods as ligation, stapling and hand interrupted suture. The operated thoracic cavities. the stumps inside and outside, the relationship between [he thoracic cavities and stumps during the operation and the hydrostatic leakage point during different periods after the operation were investigated. In addition.The stumps were histologically examined with H-E staining. The results showed the ligated stumps could resist higher pressure as compared with other techniques, suggesting the ligation was the simplest, quickest and safest method among these three methods.