| 氟康唑胶囊的溶出度考察 |
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| 引用本文： | 杨春秀,井春梅,沈素,王晓华.氟康唑胶囊的溶出度考察[J].儿科药学杂志,2001,7(3):8-9. |
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| 作者姓名： | 杨春秀 井春梅 沈素 王晓华 |
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| 作者单位： | 北京首都医科大学附属北京友谊医院药剂科 |
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| 摘 要： | 目的:通过体外溶出度的测定,对不同厂家氟康唑胶囊进行质量评价。方法:采用桨法测定溶出度,并对其溶出参数(Td、T50、m)进行统计处理。结果:不同厂家的产品之间,溶出速率相差很大(P＜0.01),B厂溶出最快,A厂最慢。结论:不同厂家的产品内在质量有显著差异。
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| 关 键 词： | 氟康唑胶囊 溶出度 桨法 |
| 文章编号： | 1009-6884(2001)03-0008-02 |
Investigation on the dissolubility of fluconazole capsule in vitro |
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| YANG Chunxiu,JING Chunmei,SHEN Su,WANG Xiaohua.Investigation on the dissolubility of fluconazole capsule in vitro[J].Journal of Pediatric Pharmacy,2001,7(3):8-9. |
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| Authors: | YANG Chunxiu JING Chunmei SHEN Su WANG Xiaohua |
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| Abstract: | Objective: Determine the dissolubilities of fluconazole capsules produced by different factories and compare them. Method: Using oar method determine the dissolubilities and the dissolution parameter(Td. T50. m) were processed statistical-ly. Results: There were significant differences in dissolubility between the products from different - factories( P < 0. 01), factory B dis-solved most quickly, factory A did most slowly. Conclusion: There were significant differences in quality between the fluconazole capsules produced by different factories. |
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| Keywords: | Fluconazole capsules Dissolubility Oar |
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