| 灵芝孢子多糖抗移植性肿瘤实验研究 |
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| 引用本文： | 高凌,亢寿海,张能芳,顾奎兴,张琴芬,钱新华.灵芝孢子多糖抗移植性肿瘤实验研究[J].药学与临床研究,2005,13(6):7-8. |
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| 作者姓名： | 高凌 亢寿海 张能芳 顾奎兴 张琴芬 钱新华 |
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| 作者单位： | 江苏省肿瘤防治研究所,江苏省肿瘤防治研究所,江苏省肿瘤防治研究所,江苏省肿瘤防治研究所,江苏省肿瘤防治研究所,江苏省肿瘤防治研究所 |
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| 摘 要： | 目的 研究灵芝孢子多糖的抗癌作用。方法 采用小鼠抗移植性肿瘤实验方法。结果 灵芝孢子多糖分别以150 mg·kg-1、300 mg·kg-1和600 mg·kg-1剂量连续12天灌胃给药,对小鼠移植性肝癌Heps的抑瘤率为53.77%～65.25%;连续8天灌胃给药,对小鼠移植性肉瘤S180的抑瘤率为50.39%～55.04%,皆呈良好的抑瘤作用。灵芝孢子多糖可分别提高Heps和S180荷瘤小鼠的脾指数和胸腺指数。结论 灵芝孢子多糖有良好的抑瘤作用,并可增强Heps和S180荷瘤小鼠的非特异性免疫功能。
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| 关 键 词： | 灵芝孢子多糖 抗肿瘤 Heps S180 |
| 文章编号： | 1007-306（2005）06-07-02 |
| 收稿时间： | 2005-10-17 |
Antitumor Effects of Ganoderma Spore Polysacchoride on Experimental Tumor |
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| GAG Ling,KANG Shou-Hai,ZHANG Neng-Fang,GU Kui-Xing,ZHANG Qin-Feng and QIAN Xing-Hua.Antitumor Effects of Ganoderma Spore Polysacchoride on Experimental Tumor[J].Pharmacertical and Clinical Research,2005,13(6):7-8. |
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| Authors: | GAG Ling KANG Shou-Hai ZHANG Neng-Fang GU Kui-Xing ZHANG Qin-Feng and QIAN Xing-Hua |
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| Abstract: | AIM To study the antitumor effects of Ganoderma spore polysacchoride.METHODS Using the model of implanted-tumor in mice.RESULTS The inhibitory rate of Ganoderma spore polysacchoride inhibit rate on Heps and S180 reached 65.25% and 55.04%;Ganoderma spore polysacchoride also improve the index of spleen and thymus in tumor-bearing mice.CONCLUSION Ganoderma spore polysacchoride has relative antitumor effects. |
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| Keywords: | Ganodenna spore polysacchoride Antitumor Heps S180 |
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