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Infantile motor neuron disease with autonomic dysfunction and bunina bodies |
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| Authors: | B. A. Semmekrot P. Wesseling J. F. M. Bruinenberg F. M. Gabreëls H. ter Laak R. C. A. Sengers |
| Affiliation: | (1) Department of Pediatrics, Division of Neonatology, University Hospital Nijmegen, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands Tel.: 31-24-3613936; Fax: 31-24-3619123, NL;(2) Department of Pathology, University Hospital Nijmegen, Nijmegen, The Netherlands, NL;(3) Department of Child Neurology, University Hospital Nijmegen, Nijmegen, The Netherlands, NL;(4) Department of Neurology, University Hospital Nijmegen, Nijmegen, The Netherlands, NL |
| Abstract: | A 2-month-old girl developed motor neuron disease (MND) with autonomic disturbances and died at the age of 5 months. Neuropathological examination revealed Bunina bodies (BBs) in the lower motor neurons of the lumbar spinal cord. The significance of the presence of BBs and the classification of the MND in this child are discussed. Received: 28 April 1997 / Accepted: 8 July 1997 |
| Keywords: | Infant Bunina bodies Autonomic dysfunction Motor neuron disease Amyotrophic lateral sclerosis |
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