食管间质瘤的临床特点及病理改变 |
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引用本文: | 哈英娣,李宁,杨艳丽.食管间质瘤的临床特点及病理改变[J].陕西肿瘤医学,2009,17(12):2331-2333. |
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作者姓名: | 哈英娣 李宁 杨艳丽 |
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作者单位: | 兰州军区总医院病理科,甘肃兰州730050 |
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摘 要: | 目的:了解食管间质瘤的特殊临床病理改变。方法:收集21例食管间质瘤的临床病理资料,每例常规光镜切片观察,作免疫组织化学SMA,S100,CD34,CD117,CKp抗体等标记。结果:食管间质瘤临床症状以吞咽困难为主,肿瘤直径〈3.0cm者17例,〉6.0cm的4例。肿瘤无出血坏死,瘤细胞以梭形细胞为主,核分裂0—4个/50HPF。免疫组化染色:CD34阳性20例(20/21),CD117阳性(20/21),SMA阳性20例(20/21),S100蛋白阳性1例(1/21)。结论:食管间质瘤临床症状与食道癌相似,病理改变以良性肿瘤为主。
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关 键 词: | 胃肠间质瘤 食管 免疫组化 组织学 |
Clinicopathologic study of gastrointestinal stromal tumors in esophagus |
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Institution: | HA Ying - di, LI Ning, YANG Yan - li( Lanzhou General Hospital,Lanzhou Command PLA,Lanzhou 730050, China.) |
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Abstract: | Objectlve:To investigate the clinicopatholgic feature of gastrintestinal stromal tumors (GISTs) in esophagus. Methods: For 21 FIST cases to observe the feature by light and immunohistochemical assays of CD34, CD117,SMA,S100 and CKp were tested. Results: All 21 cases were benign. The GISTS of esophagus showed spindie cell type in most specimens. CD117 ,CD34 and SMA were positive in most cases. Conclusion: The symptoms of GISTS in esophagus were similar as esophageal carcinoma. Pathologic features were benign. |
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Keywords: | gastrintestinal stromal tumors (GISTs) esophagus immunohistchemistry histology |
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