急性高血糖脑卒中后抑郁患者的特点和临床转归

目的:分析急性高血糖脑卒中抑郁患者的特点,并探究其临床转归情况。方法:从我院接收的急性高血糖脑卒中患者中抽选出92例作为本次研究的分析对象,其中,46例为急性高血糖脑卒中抑郁患者(观察组),其余46例为普通高血糖脑卒中患者(对照组)。患者入院后,分别观察其临床症状的差异情况,并采用日常生活能力评定(ADL)与简明智能量表(MMSE)分别评价两组患者的日常生活能力与认知功能情况。给予两组患者相同的急性高血糖脑卒中治疗方案,且比较两组患者治疗前后的脑卒中神经功能缺损以及相应的临床转归情况。结果:与对照组相比,观察组存在明显的情绪低落、焦虑、食欲减退、失眠或睡眠倒错等临床症状,其ADL评分明显高于对照组(t=3.27,P0.05);MMSE评分明显高于对照组(t=5.38,P0.05)。观察组患者的神经功能缺损评分下降幅度较小,且痊愈率、缠绵率明显高于对照组的对应值;其死亡率、后遗率明显低于对照组(χ~2=15.525;P0.05)。结论:与急性高血糖脑卒中相比,急性高血糖脑卒中抑郁患者的疾病情况更加严重,治疗治疗过程中,其经功能缺损情况恢复速率较为缓慢,且临床转归情况不甚理想。

Characteristics and Clinical Outcome of Patients with Acute Hyperglycemia Post Stroke Depression

Objective:To analyze the characteristics of patients with acute hyperglycemia stroke depression and to explore its clinical outcome.Methods:A total of 92 cases were selected from acute hyperglycemia of stroke patients in our hospital,in which 46 cases of acute hyperglycemia of stroke patients with depression were divided into observation group,and 46 cases of normal high blood glucose in patients with stroke were divided into control group.After admission,the differences of clinical symptoms were observed,and ADL scale and MMSE scale were used to evaluate the ability of daily living and cognitive function of the two groups.The two groups of patients with the same acute stroke treatment program,and were compared in neurological deficits and corresponding clinical outcomes before and after treatment.Results:Compared with the control group,the observation group had obvious depression,anxiety,loss of appetite,insomnia or sleep perversion and other symptoms;The ADL score in the observation group was significantly higher than the control group(t =3.27,P＜0.05);The MMSE score was significantly higher than the control group(t =5.38,P＜0.05).The observation group patients with neurological deficit score decreased slightly,and the recovery rate,lingering rate in the observation group was significantly higher than the corresponding values of the control group;the mortality rate,after leaving rate in the observation group were significantly lower than those in the control group(x2 =15.525;P ＜ 0.05).Conclusion:Compared with acute hyperglycemia in patients with acute stroke disease,hyperglycemia of stroke depression is more serious,the treatment process and the function defect recovery rate are relatively slow,and the prognosis is not ideal.