不同方法治疗早产儿原发性呼吸暂停疗效观察

目的：观察鼻塞式持续气道正压通气、纳洛酮、氨茶碱治疗早产儿原发性呼吸暂停的疗效。方法：将应用氨荼碱2d后仍反复出现呼吸暂停的早产儿102例，随机分为3组，各34例，分别给予鼻塞式持续气道正压通气、纳洛酮、氨荼碱治疗3d，对三组治疗效果进行比较。结果：鼻塞式持续气道正压通气组总有效率为97．1％，纳洛酮组、氨茶碱组总有效率分别为73．5％、61．8％。经x^2检验，鼻塞式持续气道正压通气组与后两组相比，差异有统计学意义（P〈0．01）；纳洛酮组、氨茶碱组相比差异无统计学意义（P〉0．05）。结论：鼻塞式持续气道正压通气治疗早产儿原发性呼吸暂停疗效优于纳洛酮、氨茶碱。

Therapeutic effect of different ways on treatment of premature infants with apnea

Objective To observe the therapeutic effect of nasal continuous positive airway pressure,naloxone and aminophylline in treatment of premature infants with apnea.Methods One hundred and two cases treated with aminophylline were randomly divided into three groups,34 cases in each group.They were respectively treated with nasal continuous positive airway pressure,naloxone and aminophylline for 3 days.The therapeutic effects were compared in three groups.Results Total effective rate was 97.1% in nasal continuous positive airway pressure group,which was obviously higher than naloxone group(73.5%) and aminophylline group(61.8%),respectively(P<0.01).There was no statistic difference between naloxone group and aminophylline group(P>0.05).Conclusion Nasal continuous positive airway pressure is superior to naloxone and aminophylline for premature infants with apnea.