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荧光定量PCR检测HBV-DNA
引用本文:周建华,万小涛,蒋维国,廖常贵.荧光定量PCR检测HBV-DNA[J].川北医学院学报,2003,18(4):106-107.
作者姓名:周建华  万小涛  蒋维国  廖常贵
作者单位:内江市第一人民医院,四川,内江,641000
摘    要:目的 探讨血清HBV-DNA水平与HBV标志物(HBVM)表现模式的关系。方法对1223例慢性乙型肝炎患者进行血HBV-DNA荧光定量PCR分析,HBVM检测采用ELISA法。结果血清HBV-DNA水平与HBV M表现模式有关,HbsAg与HbeAg的存在影响HBV-DNA水平变化。结论HbeAg水平与HBV-DNA有明显的相关,抗-Hbc、抗HBc阳性者病毒未完全停止复制,只是复制水平降低。

关 键 词:乙型病毒性肝炎  乙肝病毒标志物  DNA  PCR  荧光定量
文章编号:1005-3697(2003)04-0106-01
修稿时间:2003年10月15日

Nucleic acid Puantifying Assay of Hepatitis b virus and its Clinical signifi-cance
ZHOU Jian-Hua,WAN Xiao - tao,JIANG Wei - guo,LIAO Chang - gui.Nucleic acid Puantifying Assay of Hepatitis b virus and its Clinical signifi-cance[J].Journal of North Sichuan Medical College,2003,18(4):106-107.
Authors:ZHOU Jian-Hua  WAN Xiao - tao  JIANG Wei - guo  LIAO Chang - gui
Abstract:Objective To explore the relation between the nucleic acid content of hepatitis B Virus and hepatitis Bvirus markers. Methods: 1207 patients Suffering from Chronic hepatitis B were detected by ELISA Results: Serum HBV HDA content was related to hepatitis B virus markers. Conclusions:There is a Significant correlation between HbeAg and HBV - DNA, but positive Anti - Hbe and Anti - HBc have copies lower coyer.
Keywords:hepatitis B virus  HBVM  HBV-DNA  amplisensor
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