天津市2005-2006年HIV抗体人群筛查情况分析

目的分析天津市2005-2006年人群艾滋病病毒(HIV)抗体筛查检测数据,初步评估现行的筛查检测策略。方法对天津市艾滋病检测筛查实验室送检的601份样品,依据《全国艾滋病检测技术规范(2004年版)》规定的检测流程与方法进行HIV抗体确认。结果2005-2006年共对365份送检样品进行了确认试验,有215份为全条带阳性,确认为HIV抗体阳性。24份为特殊条带阳性,其中10例进行了随访,7例确认为HIV抗体阳性,3例排除HIV感染。51份确认试验结果为不确定,其中8例进行了随访,结果均确认为HIV抗体阴性。结论在医疗机构门诊及术前患者、公安和司法系统被监管人员等常规体检中,进行HIV抗体筛查是发现HIV感染者重要途径。对于不确定型、特殊阳性带型样品应慎重下结论,在随访检测的同时应积极考虑其他辅助手段。

Outcomes of mass screening for HIV antibody in Tianjin from 2005 to 2006

Objective To analyze the data of HIV antibody mass screening in Tianjin from 2005 to 2006 and to evaluate current screening strategy.Methods Confirmation tests were conducted for 601 samples received form HIV screening laboratories in Tianjin in line with the procedures and methods defined by the National Guideline for HIV/AIDS Detection.Results Of the 601 samples,215 were HIV antibody positive(with complete bands);24 samples were positive with special reactive blots,of which 10 cases were followed up with 7 confirmed to be infected with HIV and with 3 confirmed to be excluded;51 samples were uncertain with indeterminate blots,of which 8 cases were followed up and all were proved to be HIV antibody negative.Conclusion Routine HIV screening as part of medical examinations for patients in health care settings or for detained personnel in police and judicial organizations represents an important approach to detect cases of HIV infection,Samples with special reactive blots or indeterminate blots should be handled with caution;they should be followed up and may be tested by other approaches,such as blot test or viral genome detection.