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Colonic Vascular Anomalies and Colon Cancer in Neurofibromatosis: Report of a Case |
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| Authors: | James J Wood MRCS Robert J Longman FRCS Nicholas Rooney FRCPath Eric J Loveday FRCR Alan M Roe FRCS |
| Institution: | (1) Department of General Surgery, Southmead Hospital, Bristol, BS2 5NB, United Kingdom;(2) Department of Histopathology, Southmead Hospital, Bristol, United Kingdom;(3) Department of Radiology, Southmead Hospital, Bristol, United Kingdom |
| Abstract: | We report a case of neurofibromatosis with synchronous adenocarcinomas in the sigmoid and transverse colon. There was widespread intimal proliferation in arteries in the region of the tumors and also in the cecum. Such vascular lesions are associated with von Recklinghausen’s disease. The cecal lesion produced mural thickening visible on computed tomography. This case supports a possible genetic link between neurofibromatosis and adenocarcinoma of the colon. |
| Keywords: | Colorectal Adenocarcinoma Neurofibromatosis Vascular lesion |
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