烧伤感染创面细菌学变化及其危险因素的Logistic回归分析

目的：探讨烧伤创面感染细菌菌种及其耐药性的变化，分析影响烧伤创面感染的高危因素。方法：调查分析456例烧伤患者创面感染细菌学情况及创面感染的相关因素，并对可能危险因素进行Logistic回归分析。结果：烧伤患者456例，发生感染76例，感染率为16．67％，共分离出非重复菌株173株，其中革兰阴性菌占51．11％；药敏试验显示多数细菌呈多重耐药性；休克、吸入性损伤、伤后人院时间、抗生素应用是烧伤创面感染的高危因素，早期肠内营养为保护因素。结论：多数细菌对常用的抗生素有多重耐药性；加强烧伤患者及早就医的意识，积极有效的抗休克治疗，合理使用抗生素是降低感染发生率的关键。

Diversification of bacteria strains and logistic regression analysis of risk factors in burn infection

Objective： To analyze the strains of bacteria in burn infection, their resistance to antibiotics and risk factors of bacteria infection in the burn area. Methods： 456 inpatients with burn were investigated by surveying the pathogens in burn infection and possible risk factors , and these factors were analyzed by logistic regressive analysis. Results： 173 strains of bacteria were isolated from burn wound in 456 patients, among which 97 strains were gram negative bacteria （51.11%）. Drug sensitivity tests show that the sensitivity of pseudomonas to netilmicin and ceftazidime was in a low level, and the sensitivity of enterobacteriaceae to imipenem was still in a low level. All gram positive bacterias were sensitive to vancomycin.The high risk factors of burn infection were early shock, inhalation injury, admission time after injury and antibiotic. Conclusion： Most of the isolated bacterias show multiple resistance to antibiotic;It is the key to reducing the incidence of infection, strengthening important of early treatment, active and effective anti-shock therapy, rational use of antibiotics.