| 妇康宁片药物成分的定性鉴定与芍药苷含量测定 |
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| 引用本文： | 宋前流,胡双丰. 妇康宁片药物成分的定性鉴定与芍药苷含量测定[J]. 现代实用医学, 2009, 21(7): 696-697,701 |
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| 作者姓名： | 宋前流 胡双丰 |
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| 作者单位： | 宁波天一职业技术学院,浙江宁波,315100;宁波市药品检验所,浙江宁波,315040 |
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| 摘 要： | 目的增订妇康宁片质量检测项目,旨在提高和完善现行标准。方法采用显微和薄层色谱（TLC）技术,拟定了君药与臣药两项定性鉴别,显微鉴别目标选定白芍、香附、当归及三七,TLC鉴别益母草;用RP-HPLC法测定制剂中芍药苷含量,色谱柱为Hypersil C18,流动相：甲醇-水（40︰60）,检测波长230nm。结果定性鉴别专属性强;定量分析所含的芍药苷能与其他成分达到基线分离,芍药苷在0.228～4.560μg内呈良好的线性关系（r=0.9997）,平均加样回收率为100.72%,RSD=2.03%（n=5）。结论本法操作简便,结果准确,具有较好的重现性与稳定性,可较全面地对妇康宁片加以质量控制。
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| 关 键 词： | 妇康宁片 白芍 益母草 质量控制 |
Study on Revised Quality Standards of Fukangning Tablets |
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| SONG Qianliu,HU Shuangfeng. Study on Revised Quality Standards of Fukangning Tablets[J]. Modern Practical Medicine, 2009, 21(7): 696-697,701 |
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| Authors: | SONG Qianliu HU Shuangfeng |
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| Affiliation: | 21.Ningbo Tianyi Vocational and Technical College;Zhejiang 315100;China;2.Ningbo Institute for Drug Control;Zhejiang 315040;China |
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| Abstract: | Objective To increase a new testing protocol for the quality control of Fukangning Tablets,de-signed to enhance and improve the existing standards.Methods Two qualitative identifications of the Jun medicine and Chen medicine were worked out using microscopic and thin-layer chromatography(TLC)technology.Radix Paeoniae Alba,Rhizoma Cyperi,Angelica sinensis and Radix Notoginseng can be identified by Microscopic method and Herba Leonuri can be identified by TLC;RP-HPLC Method was established for determination o... |
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| Keywords: | Fukangning Tablets Radix Paeoniae Alba Herba Leonuri Quality control |
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