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Rapamycin selectively inhibits expression of an inducible keratin (K6a) in human keratinocytes and improves symptoms in pachyonychia congenita patients
Authors:Robyn P. Hickerson   Devin Leake   Lana N. Pho   Sancy A. Leachman  Roger L. Kaspar  
Affiliation:aTransDerm, Inc., Santa Cruz, CA, USA;bThermo Fisher Scientific, Dharmacon Products, Lafayette, CO, USA;cUniversity of Utah, Salt Lake City, UT, USA
Abstract:
Keywords:Sirolimus   TOP mRNA   mTOR inhibitor   Translational regulation
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