| 二甲基亚砜,别嘌呤醇对大鼠应激性损伤的保护作用 |
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| 引用本文： | 黄林邦 张文峰. 二甲基亚砜,别嘌呤醇对大鼠应激性损伤的保护作用[J]. 赣南医学院学报, 1994, 14(1): 1-4 |
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| 作者姓名： | 黄林邦 张文峰 |
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| 基金项目： | 江西省科委二级计划课题 |
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| 摘 要： | 从牙周病厌氧菌单克隆抗体的杂交瘤细胞株出发，通过基因工程方法－ＰＣＲ技术，调出其抗体的重链和轻链基因可变区序列，体外重组后得到单链抗体ＳｃＦｖ片段，克隆到了ｐＣＡＮＴＡＢ５载体上，在Ｅｓｃｈｅｒｉｃｈｉａ ｃｏｌｉ ＴＧ１中得到成功表达
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| 关 键 词： | 二甲基亚砜 别嘌呤醇 药理学 损伤 |
The protection of Dimethylsulfoxide and Allopurinol against stress-induced injuries in rats |
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| Huang Linbang,et al. The protection of Dimethylsulfoxide and Allopurinol against stress-induced injuries in rats[J]. Journal of Gannan Medical College, 1994, 14(1): 1-4 |
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| Authors: | Huang Linbang et al |
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| Affiliation: | Department of Pathophysiology.Gannan Medical College |
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| Abstract: | We made a few observations on dimethylsulfoxide(group A),allopurinol(group B)and their combination(group C)against stress-induced injuries in the rats which have undergone cold-restraint-stress.In comparison with saline group(group D),it is showed that the lipid-peroxidation and stress-induced injuries in stomach and lungs can be alleviated in group A and B(P<005)and dimethysulfoxide and allopurinol can provide a certain protection for the rats during stress. |
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| Keywords: | Dimethylsulfoxide/pharmacoloqy Allopurinol/pharmacoloqy Dimethylsulfoxide/pharmacokinetics Allopurinol/pharmacokinetics Lipid Peroxides/metabolism Lung/injuries Stomach/injuries Animal laboratory Stress Rats |
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