颅脑损伤患者血清促红细胞生成素的测定及其意义

目的:探讨急性颅脑损伤患者血清促红细胞生成素(EPO)含量与颅脑损伤程度的关系.方法:选择颅脑损伤120例,按损伤程度分轻、中、重三型,即颅脑损伤轻型组、中型组、重型组;选择30位健康武警战士作为对照组.均采用酶联免疫吸附法(ELISA法)检测血清EPO含量,并进行对比分析.结果:血清EPO含量:颅脑损伤轻型组、中型组与对照组比较差异具有非常显著的统计学意义(P＜0.01);重型组与对照组比较差异有显著性统计学意义(P＜0.05). 结论:急性颅脑损伤,尤其是轻、中型急性颅脑损伤可刺激机体产生EPO,EPO的含量可提示急性颅脑损伤的程度.

A Study on the Content of Serum Erythropoietin of Brain Injury

Objective:To study the correlation between the content of serum Erythropoietin and the severity of the patients with brain injury.Methods:The serum specimens of 120 cases of brain injury during March 2005 and December 2007 were collected.30 healthy policemen were chosen as the control group and their EPO content in serum were detected by Engyme linked immunosorbent assay(ELISA).Results:There is a significant difference in serum Erythropoietin between that of the brain injury patients and the control group(P<0.01).Also there is a significant difference in serum Erythropoietin between the severity of brain injury and that of the control group(P<0.05).Conclusion: EPO plays an important role in the brain injury patients.Brain injury stimulates the body to generate EPO,the content of which is a good indicator of the severity of brain injury.