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盐酸地芬尼多含量测定方法探讨
引用本文:曹凤习,杜增辉,苗翠翠.盐酸地芬尼多含量测定方法探讨[J].中国药师,2009,12(6):740-741.
作者姓名:曹凤习  杜增辉  苗翠翠
作者单位:1. 河北省药品检验所,石家庄,050011
2. 华北煤炭医学院
摘    要:目的:建立革除汞盐的非水电位滴定法测定盐酸地芬尼多含量的方法。方法:建立了以冰醋酸与醋酐(1:3)为溶剂的高氯酸非水电位滴定法测定盐酸地芬尼多的含量。结果:本法与《中国药典》2005年版二部方法测定结果一致。本法可代替原方法。结论:方法操作简单,准确可靠,可用于盐酸地芬尼多的含量测定。

关 键 词:盐酸地芬尼多  含量  测定方法  非水电位滴定

Methods for Determination of Difenidol Hydrochloride
Cao Fengxi,Du Zenghui,Miao Cuicui.Methods for Determination of Difenidol Hydrochloride[J].China Pharmacist,2009,12(6):740-741.
Authors:Cao Fengxi  Du Zenghui  Miao Cuicui
Institution:Cao Fengxi, Du Zenghui, Miao Cuicui(1. Hebei Province Institute for Drug Control, Shijiazhuang 050011 ,China; 2. North China Coal Medical College)
Abstract:Objective: To develop a method of replacing mercuric acetate for the determination the content of difenidol hydrochloride by non-aqueous potentionmetric titration. Method: The method was added glacial acetic acid and acetic anhydride ( 1 : 3 ) as solvent for perchloric acid potentiometric tiration. Result: The results of the method in the article were same with that of the method compiled in ChP,2005. eds Vol Ⅱ, and the current method could be replaced by the new method. Conclusion: The method is simple, accurate, it can be used for the determination of difenidol hydrochloride.
Keywords:Difenidol hydrochloride  Content  Methods for determination  Non-aqueous potentiometric titration
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