| 胃癌高发区庄河咸猪肉致突变性研究 |
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| 引用本文： | 林慧芝,陈跃.胃癌高发区庄河咸猪肉致突变性研究[J].中国医科大学学报,1993,22(1):22-25. |
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| 作者姓名： | 林慧芝 陈跃 |
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| 作者单位： | 中国医科大学肿瘤研究所
(林慧芝，袁媛，高华，张荫昌)，北京市肿瘤防治研究所
(陈跃，邓大君，潘凯枫)，北京市肿瘤防治研究所(张彤) |
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| 摘 要： | 通过生物学短期试验,研究了辽宁省胃癌高发区庄河地区居民自腌咸猪肉的致突变作用。结果表明:非亚硝化的成猪肉可诱发V_(79)细胞微核率(MNR)及核细胞率(MNCR)作用;但不能诱发V_(79)细胞DNA程序外合成(UDS),进一步分析亚硝化咸肉中仅有微量N—亚硝酰胺,但无致S.Typhirnurum TA_(100)回变作用
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| 关 键 词： | 胃癌 致突变性 |
STUDY ON THE MUTAGENICITY OF EXTRACTS OF SALTY PORK FROM HIGH RISK AREA OF STOMACH CANCAR |
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| Lin Huizhi,Yuan Yuan,Chen Yue et al.STUDY ON THE MUTAGENICITY OF EXTRACTS OF SALTY PORK FROM HIGH RISK AREA OF STOMACH CANCAR[J].Journal of China Medical University,1993,22(1):22-25. |
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| Authors: | Lin Huizhi Yuan Yuan Chen Yue |
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| Institution: | Cancer Institute |
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| Abstract: | The mutagenicity of salty pork (SP) sample from Zhuanghe, a high gastric cancer area in Nouth China was investigated with the biologic short- term tests. The results indicated that extract of SP did not mark mutagenic toward S. Lyphinecrium TA_(100), the non nitrosated SP induced microncilleus (MN) in V_(79) cell, Lut nitrosation SP did not increase. A little of N-nitrosamides were only foundin nitrosated SP. |
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| Keywords: | Stomach cancer mutagenicity |
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