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Agelasines J, K, and L from the Solomon Islands Marine Sponge Agelas cf. mauritiana |
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| Authors: | Appenzeller Jérôme Mihci Ghezala Martin Marie-Thérèse Gallard Jean-François Menou Jean-Louis Boury-Esnault Nicole Hooper John Petek Sylvain Chevalley Severine Valentin Alexis Zaparucha Anne Al-Mourabit Ali Debitus Cécile |
| Affiliation: | Institut de Chimie des Substances Naturelles du CNRS, 91198 Gif-sur-YVette, France. |
| Abstract: | Three new diterpene alkaloids, agelasine J (3), agelasine K (4), and agelasine L (5), were isolated from the marine sponge Agelas cf. mauritiana collected in the Solomon Islands. The structures of these compounds were elucidated by physical data analyses. They displayed in vitro antimalarial activity against Plasmodium falciparum. |
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