AbeM, an H+-coupled Acinetobacter baumannii multidrug efflux pump belonging to the MATE family of transporters |
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Authors: | Su Xian-Zhong Chen Jing Mizushima Tohru Kuroda Teruo Tsuchiya Tomofusa |
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Affiliation: | Department of Microbiology, Faculty of Pharmaceutical Sciences, Okayama University, Japan. |
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Abstract: | We cloned a gene, abeM, for a multidrug efflux pump from Acinetobacter baumannii using Escherichia coli as the host. Sequence analysis revealed that AbeM is a member of the MATE family of pumps. AbeM was found to be an H(+)-coupled multidrug efflux pump and a unique member of the MATE family. |
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