认知行为治疗对伴有躯体症状抑郁症的疗效对照研究

目的探讨认知行为治疗对伴有躯体症状抑郁症患者的疗效。方法将符合CCMD-3诊断标准且躯体不适症状≥3项的60例抑郁症患者,随机分为艾司西酞普兰合并认知行为治疗组和单用艾司西酞普兰组,使用汉密尔顿抑量表(HAMD)、汉密尔顿焦虑量表(HAMA)评定治疗前及治疗8周后精神症状。结果两组治疗后HAMD、HAMA评分均较治疗前显著降低(P0.05)。治疗8周末,两组间HAMD、HAMA评分差异有显著性(P0.05),合并认知行为治疗组HAMD总分、焦虑/躯体化因子分显著低于单用艾司西酞普兰组(P0.01)。结论认知行为治疗对伴有躯体症状抑郁症患者有效,尤其对改善躯体症状效果优于单用药物治疗。

A comparative study of cognitive-behavioral therapy in depressions presented with somatic complaints

Objective To investigate the efficacy of cognitive-behavioral therapy（CBT）in depressions presented with somatic complaints.Methods 60 patients,who met CCMD-3 criteria of major depression,presented with more than 3 somatic complaints were randomly divided into escitalopram combined with CBT group and escitalopram group.The efficacy were assessed with Hamilton Depression Scale（HAMD）and Hamilton Anxiety Scale（HAMA）before and after 8 weeks treatment.Results The total scores of HAMD and HAMA significantly decreased after 8 weeks treatment in both groups（P0.05）.The total scores of HAMD and the factor scores of anxiety/somatization in escitalopram combined with CBT group were significantly lower than escitalopram group（P0.05）.Conclusion CBT are more effective in treatment of depressions than escitalopram,especially in those with somatic complaints