针刺治疗头痛对血浆多巴胺-β-羟化酶(DβH)含量的影响

<正> 通过前一阶段实验,我们初步观察到,在经络疗法治疗头痛的研究中,以20%当归液刺激背部俞穴,有效患者血浆中多巴胺-β-羟化酶(DβH)含量降低,并具显著性。但针刺治疗头痛时血浆DβH含量的变化尚未见报导。为了进一步了解神经介质在针刺镇痛过程中的作用,现将针刺治疗头痛对血浆DβH含量的变化报导如下。

EFFECTS OF ACUPUNCTURE ON PLASMA DOPAMINE-β-HYDROXYLASE IN PATIENTS WITH HEADACHE

This study attempts to ascertain whether there is any relation between the plasma dopamine β hydroxylase (DβH) level and the effects of acupuncture in cases with headache. The experiments were performed on a group of 64 patients. Plasma DβH levels were measured before and 15 min after needling, using the method described by Nagatsu and Udenfriend with some modifications. Recorded at the same time were blood pressure (n=55) and pulse rate (n = 61). The CβH activity tended to decrease after needling in patients showing favorable effects, and to elevate in those showing less favorable effects, whereas both the decrease and elevation were found to be not significant statistically (p>0.05). The mean values of blood pressure and pulse rate in patients with favorable effects after needling were significantly lower than before needling. The experiments, therefore, suggest probably that the sympathetic nervous system participates to some extent in the analgesic effects of acupuncture in the headache patients.