| 情感性精神障碍事件相关电位变异与自杀行为史的相关性 |
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| 引用本文： | 王继军 陈兴时. 情感性精神障碍事件相关电位变异与自杀行为史的相关性[J]. 中华医学杂志, 2000, 80(4): 275-277 |
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| 作者姓名： | 王继军 陈兴时 |
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| 作者单位： | |
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| 基金项目： | 上海市卫生局青年课题基金 |
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| 摘 要： | 探讨情感性精神障碍患者件相关电位变异的临床意义。方法收集３９例抑郁相和２２例躁狂相患者，以３３例正常人为对照组，记录其事件相关电位Ｐ３００和ＣＮＶ。结论Ｐ３００和ＣＮＶ临床应用价值得到初步证实，自杀行为相关的生物学指标研究中需进一步重视。
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| 关 键 词： | 情感性精神障碍 事件相关电位 自杀 |
| 修稿时间： | 1999-04-02 |
Event-relatedpotentials and suicide behavior in patients with affective disorder |
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| J Wang,X Chen,F Lou. Event-relatedpotentials and suicide behavior in patients with affective disorder[J]. Zhonghua yi xue za zhi, 2000, 80(4): 275-277 |
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| Authors: | J Wang X Chen F Lou |
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| Affiliation: | Shanghai Mental Health Center, Shanghai 200030, China. |
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| Abstract: | OBJECTIVE: To investigate P300 and contingent negative variations (CNV) of patients with affective disorder and its clinical significance. METHODS: 39 depressives, 22 maniacs and 33 normal controls were included in this study. Both P300 and CNV were recorded in every subject, using a nicolet spirit instrument. RESULTS: Both depression and mania groups presented prolonged P300-P3b latency and decreased P300-P3 and CNV amplitudes compared with normal controls. Decreased P300 & CNV amplitudes were further related to the history of suicide behavior in the two patient groups. CONCLUSION: The clinical significance of event-related potentials was confirmed in this study, while the biological correlates of suicide behavior need further and intensive study. |
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| Keywords: | Affective disorder psychotic Event related potentials P300 Suicide |
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