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淋巴导向性抗癌药──油酸多相脂质体纵隔内注射的实验研究
引用本文:刘吉福 任林生. 淋巴导向性抗癌药──油酸多相脂质体纵隔内注射的实验研究[J]. 肿瘤防治研究, 1994, 21(5): 290-291
作者姓名:刘吉福 任林生
作者单位:北京军区总医院
摘    要:本研究用18只兔,纵隔内注射用油红标记的油酸多相脂质体(简称PL),不同时间处死,肉眼和镜下观察,结果是PL可广泛分布在纵隔内、胸壁、颈部和腋部,持续达2周;镜下见2小时至2周,纵隔、颈、腋区淋巴结内均可见桔红色。这表明PL是防治肺癌纵隔淋巴结癌转移的理想抗癌药。

关 键 词:抗癌药  肺癌  油酸多相脂持体  纵隔内  注射

A special lymph absorbing anti-cancer drug--Experiment study of injecting polyphase Liposome into the mediastinum
Liu Jifu. A special lymph absorbing anti-cancer drug--Experiment study of injecting polyphase Liposome into the mediastinum[J]. Cancer Research on Prevention and Treatment, 1994, 21(5): 290-291
Authors:Liu Jifu
Affiliation:General Hospital, Beijing Unit, People's Liberation Army, Beijing, 100700
Abstract:Polyphase liposome (PL) marked with oil red was injected into the mediastinum of 18 rabbits,killed at different period. The cervix,axillae and mediastinum were observed by macroscope, slicesof the lymph nodes by microscope. Results show that PL may widely distributed in the mediastinum,chest wall,cervical and axillary districts,sustained for 2 weeks. Orange colour in the lymph nodeslices of the cervix,axillae and mediastinum were observed under microscope from 2 hours to 2weeks. This suggested that PL is a ideal anticancer drug on preventing and treating the mediastinallymph nodes with cancer cell in the lung cancer.
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