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培哚普利配合中药治疗非胰岛素依赖型糖尿病肾病的临床观察
引用本文:高云飞,魏连波. 培哚普利配合中药治疗非胰岛素依赖型糖尿病肾病的临床观察[J]. 中国中西医结合肾病杂志, 2001, 2(5): 267-269
作者姓名:高云飞  魏连波
作者单位:中国人民解放军第一军医大学南方医院,广州,510515
摘    要:目的:探讨辨证培哚普利配合中药治疗非胰岛素依赖型糖尿病(NIDDM)并发肾病(DN)的临床疗效。方法:采用随机分组对照的原则,对照组用培哚普利,维生素E胶丸,治疗组用上述西药的同时,按中医辨证加服中药。2个月为一个疗程,观察24h 尿蛋白(Pro)排泄量,尿溶菌酶(Lyso),动脉(MAP)和肾小球滤过率的变化,结果:治疗组在减少24h Pro排泄量,降低尿Lyso的含量,提高GFR均显优于对照组(P=0.001,=0.002,=0.007)。结论:培哚普利配合中药是治疗NIDDM并发DN的有效方法。

关 键 词:糖尿病肾病 辨证论治 转换酶抑制剂 治疗
修稿时间:2001-01-08

The clinic effect of Chinese traditional herb combined with Perindopril in treating Diabetic Nephropathy caused by NIDDM
GAO Yunfei,WEI Lianbo Nanfang hospital of the first military medicine university,Guangzhou. The clinic effect of Chinese traditional herb combined with Perindopril in treating Diabetic Nephropathy caused by NIDDM[J]. Chinese Journal of Integrated Traditional and Western Nephrology, 2001, 2(5): 267-269
Authors:GAO Yunfei  WEI Lianbo Nanfang hospital of the first military medicine university  Guangzhou
Abstract:Objective: To discuss the clinic effect of Chinese traditional herb combined with Perindopril in treating Diabetic Nephropathy caused by NIDDM. Methods: 70 cases were divided into two groups randomly, Perindopril and vitmine E were used in both groups. Furthermore, Chinese traditional herb was used in treatment group according to different syndrome typing. After 2 months , treating , we observed the change of 24 hours , urinauy excretive rate, urinary Lyso , MAP , and GFR . Results : In treatment grop , the depressing of 24 hours , urinary excretive rate, decreasing of urinary Lyso, enhancing of GFR were more significant compared with control group. Conclusion: Chinese traditional herb combined with Perindopril was effect in treating Diabetic Nephropathy caused by NIDDM
Keywords:Diabetic Nephropathy syndrome typing ACE-inhibitor
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