不同炮制工艺制首乌对大鼠血虚模型的作用研究

目的以药效方法评价何首乌炮制工艺.方法建立大鼠血虚动物模型,比较生首乌和不同清蒸炮制工艺首乌、清蒸和黑豆汁拌蒸制首乌醇提液的药效差异.结果生首乌醇提部位无补血功效;不同炮制工艺制首乌醇提部位补血功效有差异.黑豆汁具有增强何首乌补血功效的作用,但与炮制工艺有关.结论炮制工艺直接影响制首乌补血功效.

Effect of Radix Polygoni Multifori Praeparata by Different Processing on Model of Blood Deficiency Rats

OBJECTIVE: To evaluate a proper processed method of Radix Polygoni Multiflori by pharmacodynamic action. METHODS: Model of blood deficiency rats were used in this experiment. The reagents were alcohol extracts of radix polygoni multiflori and its dreferent processing drugs made without any adjuvants in the first experiment. The reagents were alcohol extracts of te processing drugs made without any adjuvants and that made with decoction of black soybean in the second experiment. Their effecacy on model blood deficiency rats was observed. RESULTS: It was showed that some of radix polygoni multiflori praeparata could nourish the blood. The effecacy was different for alcohol extracts of variously processing drugs. Decoction of black soybean could reinforce effectiveness of radix polygoni multiflori praeparata. But it was related to the processed method. CONCLUSION: The processed method directly influences the pharmacodynamic action of radix polygoni multiflori praeparata.