| 银屑病角朊细胞中C－myc基因的异常表达 |
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| 引用本文： | 冯捷,郑玉萍,苏宝山. 银屑病角朊细胞中C－myc基因的异常表达[J]. 中国皮肤性病学杂志, 1995, 0(4) |
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| 作者姓名： | 冯捷 郑玉萍 苏宝山 |
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| 作者单位： | 西安医科大学第二临床医学院 |
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| 摘 要： | 原癌基因Ｃ－ｍｙｃ是调控细胞增殖的主要基因。本研究应用免疫组化法对２８例银屑病患者和１２例健康人角朊细胞中Ｃ－ｍｙｃ的表达丰度进行了检测。结果显示：患者Ｃ－ｍｙｃ水平明显高于正常人，并与疾病的严重程度相关。结果证明Ｃ－ｍｙｃ基因在银屑病发病过程中具有重要意义。
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| 关 键 词： | C－myc基因，免疫组化，银屑病 |
Overexpression of C-myc Gene in Psoriatic Keratinocytes. |
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| Feng jie,Zheng Yuping,Su Baoshan,. Overexpression of C-myc Gene in Psoriatic Keratinocytes.[J]. The Chinese Journal of Dermatovenereology, 1995, 0(4) |
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| Authors: | Feng jie Zheng Yuping Su Baoshan |
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| Abstract: | C-myc gene is the major gene in regulation cell proliferation.By means of immunohistochemical with SP we detected the expression of C-myc protoonocogene in keratinocytes from 28 psoriatic and 10healthy persons.The result showed that the level of C-myc gene in psoriatic patients was significantly higher than that in normal controls and increased level correlated with disease activity. Our study indicates that C-myc gene is important for pathogenesis of psoriasis. |
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| Keywords: | C-myc protooncogene Immunohistochemistry Psoriasis |
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